Coding Elements

A basic unit of heredity and a sequence of nucleotides in DNA that encodes the synthesis of a gene product, either RNA or protein.

Possible relationships:

enhancer/gene -[regulate]-> gene

gene -[transcribe_into]-> transcript

gene -[belong_to]-> gene_ontology

sequence_variant -[correlate_with]-> gene (eQTL)

gene -[express_in]-> tissue_or_cell_line

gene -[overlap/locate_in/downstream/upstream]- (any entities with coordinates)

The product of gene transcription. Due to alternative splicing, one gene might correspond to multiple transcripts. It is also the combination of introns and exons.

Possible relationships:

gene -[transcribe_into]-> transcript

transcript -[translate_into]-> protein

transcript -[include]-> exon

transcript -[overlap/locate_in/downstream/upstream]- (any entities with coordinates)

A transcript is a set of exons in GenomicKB (from Ensembl).

Possible relationships:

transcript -[include]-> exon

The product of RNA translation.

Possible relationships:

transcript -[translate_into]-> protein